Oʻzbekcha
ANTIBIOTIKLARGA CHIDAMLILIK VA ZAMONAVIY TIBBIYOTNING DOLZARB MUAMMOSI
Issue
"Ta'lim ufqlari" ilmiy-uslubiy jurnali 2026-yil 1-son
Abstract
Mazkur maqolada antibiotiklarga chidamlilikning biologik mohiyati, uning shakllanish mexanizmlari, bakteriyalarda yuz beradigan moslashuv jarayonlari hamda ushbu muammoning zamonaviy tibbiyotdagi ahamiyati yoritiladi. Antibiotiklardan nazoratsiz foydalanish, davolash kursini toʻliq yakunlamaslik, oʻz-oʻzini davolash va chorvachilikda dori vositalarini meʼyordan ortiq qoʻllash rezistent shtammlar koʻpayishiga olib kelishi tahlil qilinadi. Shuningdek, profilaktika, sanitariya-gigiyena, laborator diagnostika va aholining tibbiy savodxonligini oshirish masalalari koʻrib chiqiladi.
Keywords
Antibiotik
rezistentlik
bakteriya
mikroorganizmlar
infeksiya
mutatsiya
profilaktika
zamonaviy tibbiyot
Русский
В статье рассматриваются биологическая сущность устойчивости к антибиотикам, механизмы ее формирования, адаптационные процессы у бактерий и значение данной проблемы для современной медицины. Анализируются последствия бесконтрольного применения антибиотиков, незавершенного курса лечения, самолечения и чрезмерного использования антимикробных препаратов в животноводстве. Также освещаются вопросы профилактики, санитарии, лабораторной диагностики и повышения медицинской грамотности населения.
устойчивость
Ключевые слова: антибиотик
бактерии
микроорганизмы
инфекция
мутация
профилактика
современная медицина
English
This article discusses the biological nature of antibiotic resistance, its mechanisms, bacterial adaptation processes and its importance for modern medicine. It analyzes the effects of uncontrolled antibiotic use, incomplete treatment courses, self-medication and excessive use of antimicrobial agents in animal husbandry. The article also considers prevention, hygiene, laboratory diagnostics and improvement of public medical awareness.
antibiotic
resistance
bacteria
microorganisms
infection
mutation
prevention
modern medicine
1. World Health Organization. Global action plan on antimicrobial resistance. Geneva: WHO, 2015.
2. World Health Organization. Antimicrobial resistance: global report on surveillance. Geneva: WHO, 2014.
3. Centers for Disease Control and Prevention. Antibiotic Resistance Threats in the United States. Atlanta: CDC, 2019.
4. Murray P. R., Rosenthal K. S., Pfaller M. A. Medical Microbiology. 9th ed. Philadelphia: Elsevier, 2021.
5. Madigan M. T., Bender K. S., Buckley D. H., Sattley W. M., Stahl D. A. Brock Biology of Microorganisms. 16th ed. Pearson, 2022.
6. Davies J., Davies D. Origins and evolution of antibiotic resistance. Microbiology and Molecular Biology Reviews, 2010, 74(3), 417-433.
7. Ventola C. L. The antibiotic resistance crisis: part 1: causes and threats. Pharmacy and Therapeutics, 2015, 40(4), 277-283.
8. Oʻzbekiston Respublikasi Sogʻliqni saqlash vazirligi. Antimikrob vositalardan oqilona foydalanish boʻyicha rasmiy axborot materiallari.
9. Spellberg B., Gilbert D. N. The future of antibiotics and resistance. New England Journal of Medicine, 2014, 370(4), 299-302.
10. Levy S. B., Marshall B. Antibacterial resistance worldwide: causes, challenges and responses. Nature Medicine, 2004, 10, 122-129
